The Society of Critical Care Medicine (SCCM)  and the European Society of Intensive Care Medicine (ESICM) released the new sepsis definition  with the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Definition

Sepsis is life-threatening organ dysfunction due to dysregulated host responses to infection.  Septic shock is a subset of sepsis where underlying circulatory and cellular/metabolic abnormalities are profound enough to substantially increase mortality 

Read the full article here: Sepsis 3 JAMA, Feb 22, 2016

Criteria

qSOFA is in. A qSOFA score of 2 or 3 or a rise in the SOFA score of 2:

• Includes normal responses to infection (eg. fever and tachycardia is not dysregulated infection; it’s just infection)

• SIRS has been shown to missed severe sepsis in 1 in 8 patients (NEJM 2015)